Tetanus Antitoxin

COLORADO SERUM COMPANY
4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428
Telephone: 303-295-7527
Order Desk: 800-525-2065
Fax: 303-295-1923
Website: www.colorado-serum.com
Email: colorado-serum@colorado-serum.com
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.
TETANUS ANTITOXIN, EQUINE ORIGIN

Colorado Serum

This product is recommended as an aid in the prevention and treatment of tetanus in animals. This product was licensed prior to the requirement to establish a minimum age for use. The exact duration of passive immunity is unknown, but literature states 7-14 days.

Safety in pregnant animals is unknown.

Tetanus antitoxin is prepared from the blood of healthy horses that have been specifically hyperimmunized. It is recommended for use when a non-immunized animal suffers a deep wound that may have been contaminated with soil, following castration or docking, and other situations where tetanus infection has been a problem.

Tetanus is caused by a neurotoxin (Poison) produced by growth of Clostridium tetani, an anaerobic microorganism, in necrotic tissue.

DIRECTIONS:

Do not vaccinate within 21 days before slaughter. Shake well before use. Use entire contents when first opened. Store at 2°-8°C. Do not freeze. Do not mix with other products. Do not use in equine species.

DOSAGE & ADMINISTRATION:

1,500 units (5 ml) administered subcutaneously or intramuscularly is the recommended preventive dose. 5 ml equals 1,500 units. For treatment, administer 10,000 to 50,000 units to cattle, 3,000 to 15,000 units to sheep and swine.

TREATMENT:

Large doses of Tetanus Antitoxin may provide a beneficial response in animals already infected with tetanus, but success of treatment is not assured. Animals with slow healing puncture wounds or deep abrasions should be given a second dose of antitoxin in 7 days and additionally as deemed necessary.

Consult a veterinarian for vaccination program.

Vaccination with tetanus toxoid is recommended for healthy domestic animals not infected with tetanus to establish an active immunity for prevention against disease.

PRECAUTIONS:

Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. If user has questions, consult a veterinarian. In case of human exposure, consult a physician.

Contains phenol and thimerosal as preservatives.

FOR VETERINARY USE ONLY

THE PEAK OF QUALITY Since 1923

VLN: 188 / PCN: 6302.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216

303-295-7527

www.colorado-serum.com





Order #

1 dose (5 ml)

1,500 units

13601

10 - 1 dose (5 ml) vials

10 - 1,500 units

13603

10 dose (50 ml)

15,000 units

13604

CPN: 1101032.4COLORADO SERUM COMPANY4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428Telephone: 303-295-7527Order Desk: 800-525-2065Fax: 303-295-1923Website: www.colorado-serum.comEmail: colorado-serum@colorado-serum.comTHIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.

TETANUS TOXOID-CONCENTRATED

Colorado Serum

Adjuvanted

GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.

Safety in pregnant animals is unknown.

Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.

Each serial is tested for purity, safety, and potency in accordance with USDA requirements.

Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.

Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.

Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.

DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.

PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.

DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.

Horses: 1 ml IM

Cattle: 1 ml SC or IM

Sheep, Goats, Swine: 0.5 ml SC or IM

Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.

OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.

THE PEAK OF QUALITY SINCE 1923

VLN: 188 / PCN: 8601.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216

303-295-752

www.colorado-serum.com

Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.

FOR VETERINARY USE ONLY

Order #

10 - 1 ml vials

10 - 1 dose vials

11411

10 ml

10 doses

11415

CPN: 1101033.3